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Current Submissions in Search of Funding

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Partnership for Cures receives many project submissions in search of funding. A sample of those projects are displayed below. If you are interested in supporting one these projects, or if you have a different disease or project in mind, please contact DR. Bruce Bloom at 312-696-1366 or Bruce@4cures.org

Autism:  A diabetes drug may help.  A safe and inexpensive diabetes drug called ACTOS might help children with autism by reducing brain cell inflammation and by soothing intestinal troubles.  Doctors on Long Island have been using it with success for years.  This human clinical trial will take 18 months to complete at a cost of approximately $200,000. 

Amount raised to date: None to date

Brain Tumors:  Dietary approach to a cure.  Normal brain cells can use two sources of food energy.  Brain tumors can only use one.  Patients who restrict their intake of glucose and eat a ketogenic diet may starve their brain tumor cells to death. This animal trial will take 24 months to complete at a cost of approximately $200,000 and could quickly lead to a human clinical trial.

Amount raised to date: None to date

Diabetes:  Arthritis drug might treat Type I diabetes. Rheumatoid arthritis (RA) and Type I diabetes are both autoimmune diseases.  Researchers at the University of Chicago want to repurpose an RA drug to see if it can reverse new onset Type I diabetes in a mouse model.  This animal trial should be complete in one year, and will cost $25,000.  We have already secured $2500.  We are seeking an additional $22,500.

Amount raised to date: $125,000 Amount needed to complete funding: $50,000

Lou Gehrig’s Disease:  Old psycho-therapeutic drug might treat ALS.Lou Gehrig’s Disease, officially known as Amyotrophic Lateral Sclerosis (ALS), has no successful drug therapy.  Researchers at Northwestern University have discovered that a drug used to treat bi-polar disease might be repurposed to treat ASL.  This is a human clinical trial that should be complete in one year, and will cost $25,000. 

Amount raised to date: $2,500 Amount needed to complete funding: $22,500

Lupus:  Cure for severe lupus.  Two very safe and inexpensive drugs that have individually shown limited success against lupus appear to yield remarkable success when combined. Creation of a “mouse model” and then human clinical trials at Children’s Hospital of Philadelphia will take two years to complete at a cost of $160,000. 

Amount raised to date: $98,000 Amount needed to complete funding: $62,000

Parkinson’s Disease:  Fighting nerve damage with an external electrical stimulation.  Researchers at the University of Wisconsin Madison have discovered that safe and comfortable electrical stimulation of the tongue transmit nerve impulses that can heal the brain of Parkinson’s patients, reducing tremor and helping with balance and walking. This human clinical trial will take one year to complete at a cost of about $160,000. 

Amount raised to date: $20,000 Amount needed to complete funding: $140,000

Prostate Cancer:  Combining nature and man-made drugs.  The worst prostate cancers appear to be caused by receptors to testosterone.  Current treatment involves removing all sources of testosterone, but it doesn’t work.  Researchers at the Northwestern University in Chicago believe a combination of a fairly safe FDA approved drug and an extract of an African shrub might kill these resistant prostate cancer cells. This one year lab project would cost of $25,000 and could quickly lead to a human clinical trial.  We have already secured $2500.  We are seeking an additional $22,500.

Amount raised to date: $2,500 Amount needed to complete funding: $22,500

Stroke:  Surgical approach to brain self-repair. When a patient suffers a stroke the brain can repair itself, but most repair cells die of oxygen starvation before they can restore brain function.  A simple surgical technique might bring necessary oxygen to let the brain repair itself.  This Yale University study on animals could lead the way for human clinical trials in the next two years.  This $140,000 project is awaiting funding.

Amount raised to date: None to date

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